Low Energy Photon Therapy (LEPT) in Johns Hopkins University
July 26, 2001
To Whom It May Concern:
As principal investigator I carried out a randomized, placebo controlled, double blind study using Low Energy Photon Therapy (LEPT) for venous leg ulcers.
The study's purpose was to evaluate the efficacy of LEPT in the treatment of chronic venous leg ulcers in a rigorous study. The LEPT system was provided a controllable three-dimensional photon distribution in the ulcer area, and was provided by International Medical Instruments, Inc., Toronto
A statistically significant, substantial difference (p=0.008) in ulcer healing between real and placebo LEPT groups was observed. Within the first three weeks of therapy, the average total ulcer area decreased by 45.2% in the LEPT-treated group. During the same interval, the average total ulcer area increased in size by 24% in the placebo group (p=0.003).
Other areas of LEPT applications:
Based on the preliminary data, I advised Dr. A. Chaiton, Professor, University of` Toronto, to test the efficacy of LEPT for median nerve regeneration in patients with carpal tunnel syndrome (CTS). The results of this study showed a substantial recovery of CTS symptoms and regeneration of median nerve as measured by objective nerve conduction test. I recommended submitting the results of this study to Lancet.
Collected clinical data on LEPT for skin ulcers, musculoskeletal pain, and carpal tunnel syndrome suggest that LEPT has significant potential to become an accepted medical treatment modality for above applications. Availability of home treatment devices for LEPT could promise substantial cost savings in rehabilitation medicine.
Daniel N. Sauder, MD, FRCP(C), FACP
Professor and Chairman
Johns Hopkins University
Department of Dermatology
Baltimore, MD 21287-0900